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Therefore, Ang II may exert opposite effects on passive avoidance memory according to its interference with brain mechanisms leading to the storage or retrieval of this aversively motivated task.
Second, proteins in the same complex or pathway may exert opposite effects on a phenotype, playing as actors or repressors [18].
Genetic analysis of C. elegans has demonstrated that distinct serotonergic neurons regulate specific aspects of behavior [43] and that multiple 5-HT receptors may exert opposite effects on the same behavior [44].
Thus, KDM1 and KDM5 enzymes may exert opposite effects on postmitotic aging by targeting enzyme class-specific substrates for H3K4 demethylation.
However, since specific sphingolipids like S1P modulate particular cellular processes, while other closely related species may exert opposite effects [ 54, 132, 133], the enzymes responsible for their interconversions serve central roles in regulation of cellular metabolism and cell fate.
Similar(55)
That might be because WT TET1 may exert an opposite effect on neuronal differentiation in an enzymatic activity-dependent manner.
That is to say, these five plant hormones (NAA, 2,4-D, ABA, SA and JA) usually exert opposite effects on the regulation of ATG expression compared with GA3, implying that they may have common mechanism on regulating autophagy occurrences in the process of plant development, but differ from that of GA3.
In contrast to AgRP neurons, ARCinh neurons, a group that likely includes POMC neurons that exert opposite effects to AgRP neurons on common downstream targets, demonstrated concomitant increases in firing that may act synergistically with decreases in AgRP firing to more effectively drive these common targets.
TNAP might in fact exert opposite action to ecto-kinases on extracellular matrix (ECM) substrates.
Strains 55730 and 6475 are known to exert opposite immunomodulatory effects in vitro (see Lin et al [17]).
Intriguingly, metabolic and proteotoxic stressors exert opposite impacts on AMPK and HSF1 (Fig 5I).
Related(20)
may exert antagonistic
may exert adverse
may exert protective
may exert ignorable
may exert beneficial
may exert different
may exert regulatory
may exert conflicting
may exert fateful
may exert opposing
may exert specific
may exert great
may exert unintended
may exert distinct
may exert good
may exert important
may exert considerable
may exert negligible
may exert essential
may exert immunomodulatory
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