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Cells were identified using immunohistochemistry of human nuclear antigen and markers for terminal differentiation.
Young and old SMPCs were transfected with siSPARC, and myogenesis was evaluated by immunostaining for myogenin and MHC, which serve as markers for terminal myogenic differentiation.
SPRR proteins were originally identified as markers for terminal squamous cell differentiation where they are precursors of the cornified envelope [ 62].
In analogy with their untransformed counterpart, squamous cell carcinomas often express markers for terminal differentiation in the centre of tumour nests farthest from blood vessels (Roland et al, 1996).
Several studies have suggested that SPRRs are related to increased epithelial proliferation and malignant processes and are markers for terminal squamous cell differentiation, although they also function in nonsquamous tissues [ 14].
To determine a possible hematopoietic function of these genes, we analyzed the lymph gland phenotypes of homozygous mutant larvae at early middle and late third-instar stages using specific markers for terminal hemocyte maturation.
Similar(54)
In the course of our work, we discovered that CTCF is not solely a marker for terminal differentiation since it is nucleolar in many non-differentiated cell types.
The function of fibre cells in mole lenses was investigated using β-crystallin as a marker for terminal differentiation.
It is demonstrated that the numbers of mTECs expressing involucrin, a marker for terminal differentiated epithelium, were reduced in the Aire-deficient thymus [ 20].
Thus, ALP is a phenotypic marker for the early differentiations of osteoblasts, whereas the mineralization of extracellular matrix by Alizarin red staining is a biological marker for terminal differentiation.
This chronic bladder inflammation manifests as both lymphonodular hyperplasia in the bladder submucosa and urothelial hyperplasia, with a lack of uroplakin expression, a marker for terminal differentiation, in superficial facet cells (Hannan et al., 2010).
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