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The marker for turnover originated from proteoglycan aggrecan (CS846) and the marker for synthesis of type II procollagen (CPII).
This is the primary metabolite of PGF2α and has been used in several studies as a marker for synthesis and release of PG:s (e.g. [ 4, 3]).
Levels of a marker for synthesis of the procollagen of type II collagen cartilage (CPII), the C-propeptide of type II cartilage collagen, are elevated in RA patients [ 13, 15].
C2C, a marker for degradation of type II collagen in cartilage; C1,2C, a marker for degradation of type I and type II collagen in cartilage; CS846-epitope, a marker for aggrecan turnover in cartilage; CPII, a marker for synthesis of the pro-collagen of type II collagen cartilage.
C2C, marker for degradation of type II collagen in cartilage; C1,2C, marker for degradation of type I collagen and type II collagen in cartilage; CPII, marker for synthesis of the procollagen of type II collagen cartilage; CS846-epitope, marker for aggrecan turnover in cartilage.
Similar(55)
Collagen prolyl-4-hydroxylase resides within the lumen of the endoplasmic reticulum (ER) [ 18] and its expression is used as a marker for collagen synthesis [ 21, 22].
A high level of procollagen type I, a marker for collagen synthesis, has been detected in the serum of patients with recurrent breast cancer [ 37].
In the P-group, the marker for bone synthesis decreased rapidly during the first three months and more slowly thereafter, whereas the bone resorption markers decreased during the whole 12-month period.
To assess whether cardiomyocyte-specific p57 Kip 2 overexpression affects cardiomyocyte proliferation we performed immunofluorescence experiments with Ki-67 antibody, a marker for DNA synthesis and cell cycling in E8.5-E11.5 hearts [ 23].
Circulating endogenous synthesis cholesterol precursors (e.g., desmosterol and lathosterol) serve as markers for endogenous synthesis and plant-derived campesterol or/and sitosterol for cholesterol absorption, respectively.
It should be stated, however, that although mixed muscle protein synthesis often serves as a surrogate marker for myofibrillar protein synthesis, differential responses have been observed within each subfraction.
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