Sentence examples for many mutation carriers from inspiring English sources

Intriguingly, many mutation carriers are without any symptoms.

However, many mutation carriers who do not fulfil screening criteria have been identified before.

Between 1997 and 2001, approximately as many mutation carriers as 50% risk carriers underwent a PM.

By contrast, aHUS-associated mutant proteins effectively regulate complement in the fluid phase, which would explain the normal or near-normal circulating C3 levels in many mutation carriers.

However, it is also clear that many mutation carriers will be missed if the presence of a strong family history of breast cancer and/or ovarian cancer is used as the sole criterion to offer genetic testing.

Because many LRRK2 mutation carriers exhibit typical PD symptoms indistinguishable from idiopathic PD cases, it is hypothesized that an understanding of the biology and pathophysiology of LRRK2 will provide new opportunities to develop effective treatments of PD.

Due to the high risk of a second primary, many BRCA1/2 mutation carriers choose to undergo a prophylactic bilateral mastectomy (PBM) in the setting of unilateral disease.

However, as we expanded the kindreds, we discovered many other TERT mutation carriers with a similar phenotype.

Moreover, many of the mutation carriers had family history of various cancer types, including for instance colon and prostate cancer.

The sharp distinction between the regional pattern of PiB retention in many presenilin-1 mutation carriers [ 48] and sporadic AD (Fig.  3)—corresponding to the known patterns of Αβ aggregation in their brains makes a convincing argument for specific Aβ-driven retention of Aβ PET tracers.

Tumor grade was not selected because of many missing values, especially among mutation carriers.