Sentence examples for many mutation profiles from inspiring English sources

Recently, a European AID registry, the "Eurofever registry", has shown that a considerable number of patients with AIDs are of European ancestry [ 52], and many mutation profiles show differences when analyzed for distinct populations; that is, the MEFV E148Q mutation is frequently found in Europe, while the double heterozygosis E148Q/M694I is mainly observed in Japan [ 53].

Favero, F. et al. Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data.

In the next step, GWAMAR computes binary mutation profiles for each mutation profile.

Next, GO-based mutation profiles (GO-MP) are obtained by multiplying the mutation profile matrix by the gene profile matrix.

Many subtypes of epithelial ovarian carcinoma exist including the serous, clear cell, endometrioid, and mucinous subtypes 2. There are substantial differences in genetic risk factors and somatic mutation profiles between each of these subtypes.

We call vectors of these genetic variations as gain/loss profiles and point mutation profiles.

The first step in patient profile generation (Fig. 1) is to extract mutation profiles.

GDSC contains genomic profiles in the forms of copy number variation, gene expression and mutation profiles.

These results suggested that the genotyping-based mutation profiling platform was suitable for many clinical applications.

We developed and implemented an optimized mutation profiling platform ("OncoMap") to interrogate ∼400 mutations in 33 known oncogenes and tumor suppressors, many of which are known to predict response or resistance to targeted therapies.

However, the OncoMap platform may offer one immediate avenue by which systematic mutation profiling might be initiated to guide clinical trial design as well as use of existing targeted agents across many cancer types.