Exact(1)
Interestingly, many mutation sites resided on the surface of the viral proteins, suggesting that they could be involved in virus host interactions, such as antigen antibody interplay depicted on fig. 2 D and described in literature (Ekiert et al. 2009, 2011, 2012; Corti et al. 2011; Koel et al. 2013).
Similar(59)
Detection of genetic mutations is rather difficult to apply to cancer screening because it is necessary to examine many possible mutation sites per gene.
Because there could be many mutation and editing sites, the obtained P-values were corrected with the Benjamini-Hochberg correction method [ 39].
(c) Sequencing chromatograms of mutation sites.
No coding region mutations were detected within the amplicons covering the mutation sites.
To easily detect these mutations, restriction enzyme recognition sites were incorporated close to the mutation sites (Fig. 1b).
Recognition sites of the restriction enzymes HaeIII or MspI were incorporated into these mutation sites.
Mutation sites are underlined.
Sequencing of dissected mutated ovaries showed many mutations at the designed targeting site.
Using the RR, we can estimate how many mutations that create plausible NAGNAG sites have been eliminated by selection.
Exons 13 21 encode for one such binding site and many mutations causing retinoblastoma are found in this pocket [16].
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