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Coevolutionary analysis indicates that many functional domains in Hippo genes have coevolved with interacting functional domains in other genes.
Each laminin chain contains many functional domains, allowing the laminins to interact with various molecules in the extracellular matrix.
Proteins, including TAp73, contain many functional domains 36, 37. Generally, different protein domains allow for chemical modifications that can subsequently alter the activities and functions of the protein.
Full-Scale IQ is a composite index that averages a child's performance across many functional domains, providing an overall picture of cognitive health.
Therefore, data presented here clearly show that many functional domains in Archaea are predicted to contain various amounts of disordered residues.
The variants that would be expected to differ the greatest at the functional level from the full length species are those lacking the largest exon 11, containing many functional domains involved in protein-protein interaction.
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Drosophila melanogaster annotations define the locations of many functional protein domains.
Proteome analysis using Pfam identified many possible functional domains (Table S1).
This protein has many possible functional domains, but the largest component had homology to outer membrane adhesion-like proteins.
In natural ECMs, a large number of proteins are tandem modular proteins consisting of many individually folded functional domains that confer structural and biological functionalities.
Taken together, we traced the origin of dacts back to chordates, where many motifs and functional domains were established already.
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