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Some nodes may have many functional links with good strength.
Genetic analyses, such as targeted disruption or random tagging analysis, have suggested many functional links between gene products.
It implied that many functional links between genes, which may react to the external factors to further maintain the proper cellular functions or the tissue homeostasis in the normal group, were impaired in the CML group.
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Figure 2A shows that there were many functional connectivity links that were significant after FDR correction.
Collectively, many functional ramifications are linked tightly to mt genome architecture in vertebrates.
Furthermore, as typical for many in silico approaches, many of the suggested functional links need to be experimentally validated.
Many types of data are relevant to inferring functional links between genes, motivating the use of data integration.
A great many methods use the genomic context of genes to predict functional links between proteins.
In addition to many known protein relations, our dataset allows for the inference of previously unknown functional links.
It is important to note that many of the protein family relationships (based on co-expression) identified here are supported by functional links.
Functional links among the 26 genes were defined using the same approach as in many previous genetic interaction studies [6], [10], [14].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com