Sentence examples for major objective responses from inspiring English sources

Although a small fraction of NSCLC patients (∼10%) have major objective responses to EGFR-based therapy, the majority of NSCLC patients do not respond to EGFR-targeted therapies.

Major objective responses were observed in 24 patients (57%, 95% Confidence Interval (CI): 42 72%), including four complete responses (10%).

No major objective responses were seen and the median survival time was only 39 weeks.

No major objective responses were observed and ten patients had stable disease.

The sequential application of docetaxel after PELF chemotherapy gained major objective responses with manageable toxicity.

Furthermore, 4 of 19 patients had major objective responses to subsequent anticancer therapies given immediately after epigenetic therapy.

The major objective response rate was 47.7%95%5% confidence interval (CI), 33.8 62.1%).

A comparable response rate was observed for adenocarcinoma and squamous carcinoma patients as 8 of the 24 patients with adenocarcinoma had a major objective response (33.3%), while none of the 9 patients with squamous carcinoma had a major objective response.

Overall, 10 patients achieved a major objective response: one complete response (2.9%, 95% CI: 0 8.5%), and nine partial responses (26.5%, 95% CI: 11.7 41.2%).

A phase II study of the anti-EGFR inhibitor cetuximab monotherapy did not report any major objective response and the time to progression was only 6 months of recurrent or metastatic ACC (Locati et al, 2009b).

Identifying transcriptome modifications occurring in each cell subtype is a major objective to better decipher immune response.