Sentence examples for major cellular responses from inspiring English sources

Calcium homeostasis and ligand-dependent calcium signaling are key components of major cellular responses, including cell proliferation, differentiation or apoptosis.

Poly adenosine diphosphate-ribose polymerase-1 (PARP-1) is a multifunctional enzyme that is involved in two major cellular responses to oxidative and nitrosative (O/N) stress: detection and response to DNA damage via formation of protein-bound poly adenosine diphosphate-ribose (PAR), and formation of the soluble 2nd messenger monomeric adenosine diphosphate-ribose (mADPR).

Experimental animal studies have provided strong evidence that major cellular responses to PM exposure include oxidative stress (Manzo et al. 2012) and inflammation (Uski et al. 2012).

The NF-κB family is a tightly coordinated group of five identified transcription factors with structural homologies enabling them to be involved in two major cellular responses mainly related to stress and inflammation as well as to cancer development and progression [ 34].

Activation of p53 is a major cellular response to DNA damage [20] [20].

A major cellular response to viral infection (or other stress) is to inactivate eIF2α by phosphorylation.

Apoptosis, a major cellular response to DNA damage, is known to be regulated at the post-transcriptional level through activation of protein cascades, especially the core apoptotic machinery [17].

Notably, the Mdmx KD tumors revealed a significantly stronger staining for β-gal than the control group, implicating cellular senescence as the major cellular response to Mdmx KD.

Thus, changes in sterol levels in response to hypoxia are a major cellular response to oxygen limitation in the fungal Kingdom.

Potentiating of the oxygen-independent glycolytic pathway to comply with the energy demand, is one of the major cellular response to hypoxia [ 46].

Actin-tethered Keap1 that binds to nuclear factor erythroid 2-related factor 2 (Nrf2) constitutes a protein triad that is indispensable for induction of the phase II response, a major cellular reaction to oxidative/electrophile stress.