Sentence examples for major erythroid responses from inspiring English sources

Patients achieving a 20 g/l rise in haemoglobin concentration accounted for all major erythroid responses.

For patients classified as low risk according to the IPSS, the crude percentage (95% CL) that experienced major erythroid responses during the 13-week test period was 55% (45, 65) for ESA-naïve patients and 32% (18, 46) for prior ESA-treated patients.

As the haemoglobin response accounted for all patients with a major erythroid response, this figure also demonstrates the time to major erythroid response during the treatment period.

Among 119 patients who had a dose increase for any reason, 50 (42%) achieved a major erythroid response and an additional 20 (17%) achieved a minor erythroid response.

Patients with del 5q) MDS who achieved a major erythroid response displayed increased apoptosis and reduced microvessel density compared with patients who did not respond [ 42].

After 13 weeks of therapy, 49% of ESA-naïve patients and 26% of prior ESA-treated patients achieved a major erythroid response.

In the ESA-naïve patients, the crude percentage (95% CL) that achieved a major erythroid response was 49% (40, 57), with a minor erythroid response rate of 22% (15, 29) (Fig 2A).

The crude proportions of patients who had a major erythroid response or a minor erythroid response were summarized, and 95% CLs were constructed for the percentages of patients in each category by using the normal approximations.

In the prior ESA-treated patients, the crude percentage (95% CL) that achieved a major erythroid response was 26% (15, 37) and the crude percentage (95% CL) with a minor erythroid response was 18% (8, 27).

A haemoglobin concentration increase of ≥20 g/l from baseline (which is also the definition of a haemoglobin response) was observed in all patients with a major erythroid response.

Encouragingly, among the pooled patients with MDS with a del 5q) abnormality from the two studies [ 8, 9], transfusion independence and major erythroid response were maintained for a median duration of at least 2years [ 12].