Sentence examples for major host cell from inspiring English sources

The phosphatidylinositol-3-kinase (PI3K -dependent Akt and the mammalian target of raPI3K -dependent(PI3K/Akt/mTOR) and major hostheell signalling pathways that regulate protein synthesis, cell growth, proliferation, mammalian and survival.

Therefore, RSK and PKN family members are likely to be major host cell mediators of YopM action.

Although the mature erythrocyte is undoubtedly the major host cell infected by P. falciparum, prior results have suggested that nucleated erythroblasts can also be infected [8], [9], [10], [11].

Evidence that viral infection may be causally related to the development of IPF is the observation that expression of EBV latent membrane protein 1 (LMP-1) in alveolar cells is associated with a poor prognosis in IPF patients, and a major host cell for the virus is the alveolar epithelial cell [7].

Taken together, these results demonstrate that preadipocytes derived from a donor mouse can undergo adipogenesis in vivo without major host cell infiltration.

The elution fraction E3 (250 mM Imidazole) in both cases contained the highest amount of PfGAP50 and one major host cell protein band running at the size of the large subunit of RuBisCo.

Internalization of L. monocytogenes with non-phagocytic cells mainly occurs via two bacterial surface proteins: internalin-A (InIA) and internalin-B (InIB) that has E-cadherin and Met as their respective major host-cell surface receptors [ 101, 102].

Since Tregs are believed to be one of the major suppressive host cells that interfere with antitumor immune response, targeting GPCRs should be one of the effective measures to diminish Treg infiltration of the tumor environment thereby restoring tumor immunity.

However, the molecular mechanisms as well as major bacterial and host cell factors involved in these activities are poorly understood.

These observations suggest that SPs are being triggered at the initial stages of the interaction between L. major and the host cell.

For example, Bushman et al. performed a meta-analysis of all published HIV-1 RNAi screens in 2009 [ 24], and also identified the mediator complex and hnRNPs as major HIV-1 host cell factors in their analysis.