Sentence examples for broad host cell from inspiring English sources

The expression of TVA and EGFP could be detected in multiple cell types (such as myocytes, fat cells, fibroblasts, undifferentiated mesenchymal cells, etc). of the muscular tissues and connective tissues (Fig. S2 and data not shown), consistent with the broad host cell range of adenoviral vectors.

Later the virus was shown to have a broader host cell range with T cells as a major target and was renamed human herpesvirus 6 (HHV-6) (3, 4).

The rapid and easy generation of replication-deficient recombinant particles and the broad range of host cell infection have made alphaviruses attractive vehicles for applications in neuroscience and gene therapy.

Recently, using a spectral counting method, expression of a broad range of host cell proteins involved in cytoskeleton rearrangement, cellular metabolism, intracellular signaling and inflammation were identified to be up-regulated during penetration of the BBB by C. neoformans [ 14].

This is a particular challenge for wMel given the need to a adapt to a broader range of host cell types, host cell division rates, extracellular/intracellular environments, and ambient temperatures.

Herpes simplex virus-1 (HSV-1) is an enveloped double-stranded DNA virus of humans, which has a broad host range for animals and cell type.

Those altered proteins were functionally diverse including antibacterial NO production, prostaglandin H2 synthesis, and regulation of intracellular traffic, thereby suggesting broad impact on host cells towards Salmonella infection.

Furthermore, the extensive distribution of the primary cellular receptor for Ad, the coxsackievirus and adenovirus receptor (CAR), allows adenoviral vectors to infect a broad range of host cells which may be disadvantageous in tissues with various different cell types, like the CNS.

This leads to a very potent and broad caspase inhibition, which keeps the host cell machinery available and fit for viral amplification.

Also, bottlenecks that occur during transmission to a new host are much narrower for host-specific serovars than for broad host range serovars, and may allow cells with rearrangements to become fixed within the population.

Members of the subfamily, Alphaherpesvirinae (family Herpesviridae order Herpesvirales) have a broad host range, replicate quickly, lyse infected cells and establish latency in sensory neuron ganglia.