Sentence examples for substantial host cell from inspiring English sources

Its envelop glycoprotein (hereafter referred to as Env) is a major target for virus neutralization and can cause substantial host cell fusion.

Therefore, SteC is sufficient to induce substantial reorganization of the host cell actin cytoskeleton in the absence of other bacterial effectors and its N-terminal 200 amino acids appear to have a role in its regulation or localization.

In this simple model, the only remaining explanation for the previous observation of enhanced coinfection in Φ6 (Turner et al. 1999) is that a substantial subset of host cells are uninfectable.

This study illustrates how a parallel transcriptional survey between an intracellular microbe and its host cell may provide substantial insights into microbe physiology and host defenses.

We then asked if boosting pro-apoptotic signaling in the host cell mitochondria using ABT-737 had a substantial impact on LS-infected host cell survival.

Despite high quality standards and continual process improvements in manufacturing, host cell protein (HCP) process impurities remain a substantial risk for biological products.

It also makes sense that the differentially transcribed Ap genes in HL-60 and ISE6 are over-represented by membrane associated gene products, since survival in such disparate host cells would seem to require substantial specialization at the interface of the organism with its host cell: the bacterial membrane.

At this time point, in a substantial number of infected non-treated control cells, PbSERA3 was found in the host cell cytoplasm whereas in E64-treated cells, PbSERA3 was restricted to the parasite.

In addition, they revealed the existence of a distinct peripheral microdomain in the host cell with limited access to hemoglobin molecules indicating the concentration of substantial amounts of parasite-exported material.

Host cell invasion by the gastrointestinal pathogen C. jejuni has been reported to cause substantial tissue damage, but the molecular mechanisms involved remained widely unknown.

While substantial progress has been made in our current understanding of many of the above factors, the host cell receptors for OipA, HopZ and AlpA/B during infection are still unknown.