Sentence examples for major effector genes from inspiring English sources

Therefore, we propose that major effector genes became prominent among the AMP family during evolution.

These results maybe indicated that these genes are highly induced as the major effector genes in the antimicrobial response, while the others play supporting roles.

Whether the phenomenon of major effector genes is a common hallmark of insect AMPs or not, further investigation needed to be done will be helpful in understanding the evolution of insect immune system.

These results suggest that representative BmcecB6, BmcecD and Bmmor as the major effector genes have broad antimicrobial spectrum, strong antimicrobial activity and high microbe-induced expression among each family and maybe play crucial roles in eliminating microbial infection.

Our results further substantiate the candidacy of KIAA0319 and DCDC2 as major effector genes in DYX2, while proposing FAM65B and CMAHP as new DYX2 candidate genes.

Though much further work is needed, we postulate, based on these and previous results, that DCDC2 and KIAA0319 are the major effector genes responsible for DYX2's influence on RD and LI risk and that alteration of gene expression levels or patterns is the mechanism by which this effect is exerted.

Despite their expression in human plaques [49], several lines of evidence argue against a role of CDKN2A and CDKN2B as major Chr9p21.3 effector genes.

This gave us the first hint that Crz1p, the major effector of calmodulin/calcineurin-regulated gene expression in yeast [29], might be involved in the PUN1 regulation.

Evo-devo studies established that because of optimal pleiotropy, the gain or loss of a trait will likely proceed by the co-option of a local regulator that responds to global cues and controls a battery of effector genes, rather than a major upstream regulator or multiple downstream effectors [ 10 13].

Applying Mosaic-seq to 71 constituent enhancers from 15 super-enhancers, our analysis of 51,448 sgRNA-induced transcriptomes finds that only a small number of constituents are major effectors of target gene expression.

Following DNA damage, activation of p53 leads to transcription and upregulation of p53 target genes, among which P21 acts as the major effector of p53-induced cellular senescence.