Sentence examples for major effector cells from inspiring English sources

The immunological basis of tumor response is based on tumor-specific CD4+ T helper type 1 (Th1) in the priming phase and tumor-specific CD8+ T cells as the major effector cells.

As discussed above, neutrophils are the major effector cells that lead to early graft loss in islet transplantation.

Macrophages and lymphocytes are generally considered the major effector cells controlling the disease in vivo [7], [8] through TNF-α and IFN-γ production [9], [10].

The mast cell is one of the major effector cells in inflammatory reactions and can be found in most tissues throughout the body [1].

Neutrophils are one of the major effector cells of innate immunity since they can recognize, phagocytose and kill microorganisms using effector mechanisms that involve secretion of reactive oxygen species and cytotoxic components.

Although the population of NKT cells in PMBC was also increased by rAAV-/rAdv-hTERTC27 (Fig. 2F), the percentage of the NKT cells (6%) was too low as compared to that of NK cells (30%) to be the major effector cells which can induce such significant tumor growth suppression.

These data suggest that the fetal fibroblast is the major effector cell for scarless fetal skin repair.

CD8+ T cells were a major effector cell-type of antitumor response in the immunized mice with the Fb/B7.1/IL7/OVA cells.

These data identify the Type A macrophage-like synovial lining cell as the primary source of collagenase mRNA in vivo in the rheumatoid arthritis synovium and, potentially, as a major effector cell in the tissue destruction of the disease.

As IgE/antigen immune complexes (IgE-IC) bind to human cells through FcεRI or FcεRII/CD23 surface molecules, the present study aimed to identify which functional receptor may be involved in IgE-IC interaction with human macrophages, the major effector cell during parasite infection.

In this way, type I and II IFNs exert a pronounced and clinically important effect upon macrophages, a major effector cell of the innate immune system.