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Genome maintenance is a constant concern for cells, and a coordinated response to DNA damage is required to maintain cellular viability and prevent disease.
In this context, and considering the total metabolic, energy demand imposed by the translation process [7], it seems reasonable to assume that this process is associated with an energy source to rapidly replenish energy and maintain cellular viability.
These results suggest that nicorandil can maintain cellular viability against the challenge of R120G-induced cellular toxicity without alteration of the protein aggregate level as well as of amyloid oligomer formation.
Autophagy under these conditions may serve to eliminate oxidized and damaged proteins and organelles and thus maintain cellular viability.
Consistently elevated levels of ROS activate an adaptive stress response which enables cancer cells to survive in high ROS ambience to maintain cellular viability [ 36].
Under such growth conditions, the ability of the cell to edit m-Tyr-tRNAPhe would be essential to maintain cellular viability.
Similar(48)
The present work established an efficient staining method for fluorescence activated cell sorting (FACS) with Chlorococcum littorale maintaining cellular viability.
Thus, the newly developed VS442 vitreous solution was demonstrated to be more efficient in maintaining cellular viability and osteogenic function for vitreous cryopreservation of TEB over VS55.
HCA also maintained cellular viability, preventing stretch-induced cell death.
One explanation is that the ATP level in the FCCP treated cells was already nearing a lower limit necessary for maintaining cellular viability.
Figure 2C displays the highest inhibitor concentrations applied which still maintained cellular viability and were assumed to have the strongest effect on target activity.
Related(20)
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maintain neuronal viability
maintain basic viability
maintain cellular polarity
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com