Sentence examples for main toxic effects from inspiring English sources

The main toxic effects of the regimen consisted of skin and gastrointestinal manifestations.

The main toxic effects observed were stomatitis (34% of cycles) and neutropenia (41% of cycles).

Lead has two main toxic effects on the hematologic system: reduction of erythrocyte lifespan and decreased hemoglobin biosynthesis.

Indeed, the main toxic effects of antiglaucoma treatments reported in the literature are related to the doses of preservative commonly used in eye-drop formulations.

The incidence of main toxic effects according to the NCI-CTC grade scale are shown in Tables 2-wrap> and 3-wrap>.

23– 28 As mentioned, neutropenia, sensory neuropathy, fatigue, arthralgias, myalgias, and stomatitis are the main toxic effects associated with this agent.

Therefore, the main toxic effect of SUA is hypoglycaemia [ 24].

The main toxic effect recorded by the French group was myelosuppression, with the same proportion of grade 3 4 neutropenia, and slightly more anemia (grade 3 34%), and thrombocytopenia (grade 3 4 31%), probably as a consequence of the second-line setting.

In a phase II study, vinorelbine (30 mg m−2 D1) plus 5-FU (350 mg m−2 per day continuous infusion D1 3) in pretreated MBC patients exhibited substantial activity (ORR 43%) and acceptable tolerability, with the main toxic effect being severe neutropenia in 24% of patients (Froudarakis et al, 1998).

The main toxic effect of DON and other trichothecene mycotoxins at the cellular level in both humans and domesticated animals is the inhibition of protein synthesis by binding to the ribosome (Ehrlich and Daigle 1987; Middlebrook and Leatherman 1989a, b; Rotter et al. 1996).

Principal toxic effects were hematologic and gastrointestinal.