Presumably, this is due to differences in the toxicity of furfural compared to 5-HMF, with the former exhibiting greater toxic effects as has been reported in other microorganisms [ 27– 30].
Greater toxic effects were observed in PM 10) extracts than in PM 100) extracts, but PM 10) toxic effects were not significantly different from those in PM 100).
Given the ubiquitous expression patterns in all Utricularia organs of genes encoding detoxification enzymes, lower relative ROS detoxification is expected in traps and therefore greater toxic effects such as mutagenesis.
Because 10 μM selenite exerted greater toxic effects against PC-3 cells, which are highly metastatic and resistant to chemotherapy, further studies were carried out in PC-3 cells.
In addition, OH-PCBs are gaining more attention because they are increasingly found in environmental samples due to new analytical techniques, and they can exhibit greater toxic effects than their parent PCBs.
The water extract of LD exerted its greatest toxic effect on the HL60 cell line (human promyelotic leukaemia cell lines) killing all HL60s after 72 hours of exposure.
Therefore, inhibits the synthesis of DNA, RNA, thymidylates, and proteins, having a greater toxic effect on rapidly dividing cells.
It shows a greater toxic effect on rapidly dividing cancerous cells, which replicate their DNA much faster, than on normal cells.
Along with expression of the co-chaperone Hsp20, the up-regulation of DNA recombination and repair proteins indicates the greater toxic effect of chromate imposed on M9L-grown cells.
As previously reported by our research group [ 4], MOs exposed to 6 mg/L UP-CNTs had a greater toxic effect compared to other nanoparticles, observing an 80% decrease in cell viability.
