Sentence examples for primary toxic effects from inspiring English sources

The primary toxic effects of benzene in humans are: (1) the suppressive effects on formation of the three main types of blood cells (erythrocytes, leukocytes and thrombocytes) resulting in hematotoxicity and on the immune system; and (2) the development of AML, which are the key endpoints on which regulatory agencies such as the USEPA base their toxicological benchmarks.

Thus, exposure of the rat erythrocytes to NaF leads to impairment of the cellular antioxidant system and severe energy depletion, the latter probably being the primary toxic effect.

Its primary toxic effect is to act as a stimulant in the central nervous system.

Principal toxic effects were hematologic and gastrointestinal.

Hemorrhage is the principal toxic effect during oral anticoagulant therapy.

The concomitant treatment with Med and TRAIL showed robust apoptotic effects in primary myeloid leukemia cells but had no toxic effects in primary human peripheral blood mononuclear cells (PBMCs).

CAT enzyme plays crucial roles as antioxidants and constitutes the primary defense system against the toxic effects of superoxide radicals (O2−) in organisms [ 40].

One of the other benefits found from boesenbergin A is that it has no toxic effects against primary human blood lymphocytes.

The SOD is a group of metalloenzymes that play a crucial role as antioxidants and constitute the primary defense system against the toxic effects of superoxide radicals (O2−) in organisms [ 39, 40].

Ideally, adverse or even toxic effects on primary cells are seen early enough in preclinical studies to avoid unnecessary in vivo testings in animals or to prevent harmful exposure of human patients.

The primary outcome measure is the toxic effects on one or more of the following IVF outcome parameters: pregnancy rates, fertilization rates, and number and quality of oocytes retrieved.