Sentence examples for fold resistance from inspiring English sources

Previous experimental studies have successfully identified two important mutations (R487K and E571K) conferring 100 and 25 fold resistance to Amsacrine respectively.

Pearl-Sel shows >1000 fold resistance to spinosad compared to Geneva88 [14].

EC50s for each drug were calculated for each strain and compared to the 2004 strains in order to estimate fold resistance.

For example Luo et al. [53] observed that while MEAM1 from China remained largely susceptible to acetamiprid, imidacloprid, and thiamethoxam, MED from China expressed 20-170 fold resistance.

Fold resistance was calculated as the ratio between IC50 values in parent and pulse-selected cells.

In both cell lines the fold resistance determined was significantly higher than the fold increase in target enzyme DNA, mRNA or protein levels.

The doxorubicin-resistant A2780ADR cells showed 18-fold resistance to doxorubicin and were cross-resistant to cisplatin and carboplatin.

S1-M1-80 S1-M1-80 S1-M1-80 S1-M1-80sistant to mitoxantrone than sensitive S1 cells and displayed 150-fold resistance to topotecan.

In contrast to the doxorubicin-resistant cells, MCF-7EPI cells showed larger resistances at dose 9 (94-fold resistance to epirubicin and 39-fold resistance to doxorubicin).

Before selection, the field strain showed 3.1-fold resistance compared to the susceptible strain (CSS).

Especially, 8 displayed outstanding potency against L100I (EC50 = 17 nM with a 2.8-fold resistance ratio) and 18 was relatively more potent to E138K mutant (EC50 = 43 nM with a 4.7-fold resistance ratio).