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Exact(6)
Studies comparing pharmaceutical products from competing companies were typically short-term studies, designed for other purposes than health economic analyses, and, in general, did not use therapeutically equivalent dosing.
Table 2 compares equivalent dosing amounts based on the immediate release total daily dose.
Women generally have higher levels of EPA and DHA than men following equivalent dosing, and older women have higher levels than younger women [ 45].
This single-center retrospective cohort analysis comparing important 12-month post-transplant outcomes in near-contemporaneous cohorts receiving the extended-release or standard-release tacrolimus formulations demonstrates that these are equally efficacious and safe, and allows for equivalent dosing requirements.
Equivalent dosing of risperidone, olanzapine and quetiapine did not differ significantly before or after the switch with the exception of a single patient who was receiving a maintenance dose of 1000 mg quetiapine and switched to 10 mg of olanzapine (Table 4).
PK data for BGC9331 in our study is comparable to previous reports where the equivalent dosing schedule was administered (Plummer et al, 2003).The AUC and Cmax for BGC9331 (Table 7) in our study are comparable with this historical published data at equivalent doses and schedules.
Similar(54)
Human equivalent dose.
We used equivalent dose of zoledronate and dexamethasone.
Four subjects were administered multiple 6 mg equivalent doses of ISIS-SMNRx and up to 16 subjects will be administered multiple 12 mg equivalent doses.
Basing the dose on body surface allows for determination of an equivalent dose to another species.
Equivalent doses (200 600 μmol/kg; i.p). of phosphocholine or choline also increased serum insulin dose-dependently.
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