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Exact(54)
Although minimizing the likelihood of toxicity using TDM is important in critically ill patients, dose adaptation to avoid under-dosing and maximize efficacy is also valuable.
Most antimicrobials require dose adaptation during CRRT.
Neurological toxicity can be acute, requiring dose adaptation or a change of drugs.
This study showed that adding a PAD module to a NICU CPOE system improved both PAD evaluation and analgesia/sedation dose adaptation on the basis of the scores.
Treatment was initiated with a standard daily dose of 300 μg but dose adaptation was possible every 3 months from 150 to 600 μg daily.
No predefined dose adaptation algorithm was used.
Similar(6)
No dose adaptations will be made for study purposes.
Dose adaptations were performed as described elsewhere [ 15].
Diarrhoea peaked in cycle 2, and was reduced in the following cycles by dose adaptations.
There was a mean of 2.3 filtration dose prescriptions per patient over the observation period (due to changing clinical conditions), with a total of 77 dose adaptations.
MMF dose adaptations were initially made on the basis of tolerance and clinical response, and the inclusion MMF dose was maintained throughout follow-up.
Related(20)
level adaptation
treatment adaptation
dose responsiveness
dose adaption
shot adaptation
dosing adaptation
rate adaptation
strength adaptation
hit adaptation
feed adaptation
exposure adaptation
measure adaptation
agent adaptation
radiation adaptation
vaccination adaptation
dose adjustment
dose designation
dose Platform
dose number
dose level
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