Sentence examples for defective functioning from inspiring English sources

Our data have demonstrated that in CH during the active phase of the disease, the facilitation in temporal processing of nociceptive stimuli is linked to a defective functioning of the DMN.

In a lively and informative Perspective, Brown and Goldstein discuss the newest member of the cholesterol disease quartet, autosomal recessive hypercholesterolemia (ARH), and speculate how mutations in the ARH protein could lead to defective functioning of liver LDL receptors.

Defective functioning of the autophagic-lysosomal pathway, dysregulated mTORC1 signaling, and impaired lipid metabolism in the liver affect each other and may further exacerbate vulnerable lipid homeostasis and insulin sensitivity in obesity (Um et al., 2004; Khamzina et al., 2005; Yang et al., 2010; Samuel and Shulman, 2012; Han et al., 2015; Martinez-Lopez and Singh, 2015).

Accordingly, an ACC may result from defective functioning of any or several genes from a relatively limited set of genes required for proper neurodevelopment.

The mutant flies showed abnormalities in heavy exercises, such as climbing or flying, but not in light movements, such as locomotion, probably because some muscles and/or neuromuscular junctions had normal functioning while other muscles had defective functioning.

This could indicate the defective functioning of the motile cilia that circulate cerebrospinal fluid (62– 62).

Cloning and characterization also open new therapeutic vistas that involve correcting the defective function at the molecular level.

A deficiency of vitamin B12 often causes defective function of the intestine, resulting in indigestion and sometimes constipation or diarrhea.

It contends that Knight Capital failed to remove a defective function in one of its routers that was used to execute orders that day.

What is more, the defective function of DCAF4 could be implicated in neurodegeneration [45].

Defective function of the epithelial sodium channel (ENaC) also appears to play a key role [1, 2].