Sentence examples for defective RNAi from inspiring English sources

Loss of R2D2 results in defective RNAi.

To determine if sam4, sam12, and sam13 exhibit enhanced or defective RNAi sensitivity, we performed feeding RNAi on his-44.

In this sense, the mammalian stomatitis virus achieved increased accumulation in Caenorhabditis elegans with defective RNAi machinery [ 31].

Like other synMuv B mutants, all three alleles showed enhanced larval arrest on his-44 RNAi, suggesting that the absence of a synMuv phenotype with lin-15a RNAi cannot be attributed to defective RNAi.

However, cen1-dg:ade6+ silencing is largely unaltered in sir2Δ cells (red colonies), or in cells expressing a partially defective RNAi component (cid12-ha; subunit of the RDRC complex; Motamedi et al, 2004).

The defects observed in heterochromatin nucleation in sir2Δ, clr3Δ and swi6Δ cells is unlikely due to defective RNAi since centromeric siRNAs are still produced in these mutants (Buhler et al, 2006; Sugiyama et al, 2007) and Supplementary Figure S4B).

High salt and osmotic stresses induce autophagy in an A. thaliana, and autophagy-defective RNAi- AtATG18a plants are more sensitive to salt and drought conditions than wild-type plants, demonstrating a role for autophagy in response to these stresses.

RDE-4 facilitates processing of dsRNA by DCR-1, and rde-4 mutant animals are defective for RNAi [2], [13], [14].

TEs are mobilized in Caenorhabditis elegans mutants that are defective in RNAi [ 52, 53] and in mutants of A. thaliana that are deficient in DNA methylation and chromatin structure regulation [ 45, 54- 56].

We found that, contrary to previous reports, rde-4 mutant animals are not completely RNAi defective.

Therefore, to evaluate the potential for cross-regulation between RNA editing and RNA interference in the context of lifespan, we evaluated adr-1; adr-2 mediated declines in lifespan in the presence of the RNAi defective strain, rde-1 ne-219).