Sentence examples for by triggering the expression from inspiring English sources

Kir2.1 channel activity, which is responsible for this hyperpolarization, initiates myogenesis by triggering the expression of early transcription factors such as myogenin and myocyte enhancer factor (MEF2) [27].

P53 activates the extrinsic apoptotic pathway by triggering the expression of transmembrane protein FasL, whose receptor belongs to TNF receptor family (TNF-R) [ 13, 14].

After middle cerebral artery (MCA) occlusion, TLR 2 and TLR 4 are documented to be upregulated and contribute to tissue damage by triggering the expression of inflammatory and apoptotic genes [ 24].

FasL elicited a proinflammatory reaction in human keratinocyte HaCaT cell line and reconstructed human epidermis by triggering the expression of stress-responsive transcription factors and inflammatory cytokines in absence of an apoptotic response.

Whatever their mechanism of action, both serve to illustrate that p38 or MK2 can be activated sufficiently to have an effect upon the cell cycle and cellular replicative capacity, but not sufficiently to make this activation readily detectable by immunoblot, and thus by extrapolation potentially not sufficiently to affect cellular morphology by triggering the expression of F-actin stress fibres.

Thus we suspected the proinflammatory effect of CXCL13 which was potentially mediated by triggering the expressions of cytokines, IL-12 and IL-17, which presented for the activation of Th1 and Th17 cells, respectively.

It acts as an autocrine factor in adipose tissue by triggering the gene expression responsible for adipogenesis [ 18].

We revealed that citreoviridin induced the UPR by triggering the protein expression or phosphorylation of PERK, eIF2 α, IRE1 α, and Ero1-L α.

By triggering the over-expression of MHC-I molecules and costimulatory molecules, in vitro treatment with a combination of hIFN-γ and GGTI-298 modifies LB1319-MEL melanoma cells such that they acquire some characteristics of stimulatory APC and become more efficient stimulator cells able to activate CD8 T lymphocytes from PBMC of HLA-compatible HD.

In this sense, fruit induced resistance may have occurred by triggering the increased accumulation and expression of pathogenesis-related proteins (chitinases and glucanases) and/or heat shock proteins [ 32].

Iron overload 4 and inflammation 2, 3 stimulate hepcidin expression by triggering the mothers against decapentaplegic homolog (Smad -signaling or Smad -signalinger and activator of transignalion (Stransducerling pandwactivatorectively.