Sentence examples for by activating the expression from inspiring English sources
A more recently identified target of the IIS pathway is SKN-1, a transcription factor that orchestrates the oxidative stress response in adult C. elegans, independent of DAF-16 activity, by activating the expression of genes coding for enzymes including catalases, SODs, and some glutathione S-transferases [ 131- 133].
Furthermore, hypoxia also enhances Snail1 activity by activating the expression of its partners lysyl-oxidases (LOX) both in the kidney after UUO and in cancer cells, thereby promoting fibrogenesis and tumour progression through the reinforcement of the EMT programme (Higgins et al, 2007; Sahlgren et al, 2008) (Fig 3).
Moreover, resveratrol showed oestrogen agonist activity in MCF7 cells by activating the expression of two oestrogen-responsive genes, such as progesterone receptor (PR) and pS2 genes (Jang and Pezzuto, 1999).
Other antioxidant, curcumin activated glutathione S-transferase P1 (gene1) gexpressionsion by activating the expression of the luciferase gene from a reporter construct carrying GSTP1-ARE [ 38].
Bonnet et al. [176] showed that dichloroacetate reduced tumor cell proliferation and increased apoptosis by activating the expression of the K+ (Kv1.5) channel through nuclear factor of activated T cells and by reducing the mitochondrial membrane potential in tumor cells.
c-MYC activation was shown to activate p53, either by inducing DNA damage and/or by activating the expression of ARF.
We hypothesized that BA treatment might contribute to the maintenance of the flowering signals by activating the expressions of GI, LFY, and SOC1 and inactivating COP1 and TFL1b.
In response to sub-lethal insults, the central nervous system has the capacity to protect itself from subsequent serious injury by transiently activating the expression of survival networks.
Thus, by directly activating the expression of these EMT early drivers, P-TEFb is capable of orchestrating the EMT program to drive malignant progression.
Taken together, these results suggest that Pou3f1 promotes neural fate commitment by directly activating the expression of neural development-related genes.
FOXM1 also contributes to a number of single strand break SSB repair mechanisms by transcriptionally activating the expression of genes, such as RFC4, Exo1 and PolE2 [41].
