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It supports the conclusion that the use of hypomethylating drugs exclusively might exacerbate rather than cure cancer by unleashing the expression of hypermethylated pro-metastatic genes and converting nonaggressive breast cancers to highly metastatic aggressive tumors with low survival prognosis [ 64, 92].
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By unleashing the immune system, it sometimes led to attacks on normal cells.
Finally, a two-step artificial biosynthetic pathway was developed by unleashing the intrinsic genetic potential of E. coli.
The proposed framework advances data-driven medicine by unleashing the content of unstructured medical data in an efficient and unlimited way to be harnessed by medical experts.
The decrease of β-catenin not only attenuates Wnt signaling but also unleashes the expression of PPARγ, which is normally suppressed by β-catenin [ 38- 40].
Thus, we suggest that, MVaf induces apoptosis by sequestering DLC2 and DLC1, thereby unleashing the pair of sensitizer and activator BH3-only proteins Bmf and Bim.
But deeper partnerships with the portals could do the trick by unleashing a realm of new services.
Yet surgery makes the lesions worse by unleashing a new round of tissue destruction.
Grandal recouped a run by unleashing a homer to right field in the third.
At the site of infection, neutrophils rapidly combat pathogens by unleashing ROS and proteases.
Preservation of the epithelial phenotype depends on a direct inhibitory action on Slug (Snai2), which if unleashed drives EMT by repressing the expression of E-cadherin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com