by sequence alignment to

USAGE SUMMARY

The phrase "by sequence alignment to" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in bioinformatics or genetics, when discussing the comparison of biological sequences. Example: "The evolutionary relationships among the species were determined by sequence alignment to identify conserved regions."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

5 human-written examples

The minimal region of the functional epitope was further delineated, by sequence alignment, to be D-x-[I, L]-A-[I, L]-L-P-V-D-E-[L, I]-x-A-[L, I], where x represents any amino acids.

Journal of Immunological Methods

By sequence alignment to structurally characterized domains, the sequence boundaries of the KR and DH were determined.

Chemical Science

Besides this, on chromosome 1H the pectin methylesterase 49 (PME49) was found by sequence alignment to be associated to CSS.

BMC Plant Biology

To ensure the correct annotation, probesets from both microarray platforms, as well as MPSS tags, were mapped by sequence alignment to a human transcriptome (HTR) database that was previously used for a multiple platform comparison study [ 20, 21].

BMC Genomics

The BH3 domain predicted by sequence alignment to be present in SOUL spans residues 158 172, i.e. the last seven residues of the second α-helix of the molecule and eight amino acids in the loop connecting it to strand G.

Biochemical Journal

Human-verified similar examples from authoritative sources

Similar Expressions

55 human-written examples

All of these mutations occur at the amino acid residues predicted (by sequence alignments) to anchor the water metal ion bridge in this species.

Biochemistry

The assigned enzyme activities and annotations are supported by sequence alignments to conserved domain database profiles (CDD of NCBI; http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml), for these enzymes [ 38].

BMC Systems Biology

The completeness of transposons was confirmed by the presence of TIRs at both ends, followed by multiple sequence alignment to well-studied examples (Table 2, Figure 2).

BMC Genomics

Accordingly, we designed highly specific NASBA antisense and degenerate sense primers for a segment of 16S rRNA variable region by universal sequence alignment to simultaneously detect S. Enteritidis and S. Typhimurium.

Analytica Chimica Acta

In addition, the unique sequences associated with the innate immune response were identified by sequence alignment according to the previously public report.

Fish and Shellfish Immunology

It is likely that the CNSs have degraded over evolutionary time but the binding functions may be conserved even though they cannot be detected by sequence alignment due to binding site turnover.

Genome Biology and Evolution

Expert writing Tips

Best practice

When using "by sequence alignment to", ensure that the object you are aligning to is clearly defined. For instance, specify the database, genome, or specific sequence you are using as a reference.

Common error

Avoid using "by sequence alignment with" when the intention is to indicate the reference sequence. While "with" might seem grammatically interchangeable, "to" is more precise when indicating the target of the alignment.

Linguistic Context

The phrase "by sequence alignment to" functions as a prepositional phrase that modifies a verb or noun, indicating the method or means by which an action is performed or a result is obtained. Ludwig AI confirms its usability in written English, particularly in scientific contexts.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Wiki

0%

Ludwig's WRAP-UP

The phrase "by sequence alignment to" is a grammatically sound and usable prepositional phrase, primarily found in scientific literature. Ludwig confirms that it's a correct and reliable phrase. Its main function is to specify a methodology used for comparing biological sequences against a reference, such as a database or a genome. While it may not be universally common, its precise meaning and consistent use in scientific contexts make it an appropriate choice. When employing this phrase, clarity and precision are paramount; clearly define the object being aligned to in order to avoid ambiguity.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

using sequence alignment for

Focuses on the application of sequence alignment, rather than the method itself.

through sequence alignment of

Emphasizes the process of aligning sequences, changing the prepositional focus.

via sequence alignment with

Replaces "to" with "with", altering the prepositional relationship while maintaining the core meaning.

based on sequence alignment of

Shifts the emphasis to the foundation of the analysis resting on sequence alignment.

employing sequence alignment on

Highlights the active use of sequence alignment in a specific context.

utilizing sequence alignment for

Similar to 'using', but with a slightly more formal tone.

with sequence alignment against

Specifies that the alignment is performed against a reference, adding detail.

comparing sequences through alignment with

Makes explicit the act of comparing sequences, changing the focus slightly.

assessed via sequence alignment for

Indicates an evaluation is being made using sequence alignment.

determined from sequence alignment of

Highlights the derivation of information from sequence alignment.

FAQs

How is "by sequence alignment to" used in scientific writing?

In scientific writing, "by sequence alignment to" is used to describe a process where sequences are compared to a known reference, such as a genome or a database, to identify similarities, differences, or evolutionary relationships. It's typically used to explain how a conclusion was reached or how a specific element was identified.

What are some alternatives to "by sequence alignment to"?

Some alternatives include "using sequence alignment for", "through sequence alignment of", or "based on sequence alignment of". The best choice depends on the specific context and the emphasis you want to convey.

Is it correct to say "by sequence alignment with" instead of "by sequence alignment to"?

While "by sequence alignment with" isn't grammatically incorrect, "by sequence alignment to" is generally preferred and more precise in scientific contexts because it clearly indicates the reference sequence being aligned against. Using "by sequence alignment to" avoids potential ambiguity.

What does "sequence alignment" actually mean in the context of "by sequence alignment to"?

In this context, "sequence alignment" refers to the process of arranging DNA, RNA, or protein sequences to identify regions of similarity that may indicate functional, structural, or evolutionary relationships between the sequences. "By sequence alignment to" means that this process is being used to compare a sequence of interest to a known reference sequence.