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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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through sequence alignment of

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "through sequence alignment of" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in biology or bioinformatics, when discussing methods for comparing biological sequences. Example: "We were able to identify evolutionary relationships through sequence alignment of the DNA samples."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

Through sequence alignment of the N-terminal region of Cide and Dff family proteins in human and mouse (Fig 1a), we observed highly conserved 37 amino acid residues around the EDGT protein signature site in the CIDE-N domain and NCD.

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

Additionally, identity was confirmed through sequence alignment to orthologs, conservation of protein domains, presence of conserved and characteristic protein features and gene structure comparison.

Access information for the KLK15 gene and its protein product was downloaded from different databases as given in Additional file 1. Potential KLK15 alternative splice variants were identified through sequence alignment analysis of the splice variants and Expression Sequence Tags (ESTs) reported in publicly available databases including NCBI and Ensembl.

Science

BMC Cancer

Furthermore, the epitope was found to be highly conserved among different topotypes of serotype O FMDV through sequence alignment analysis and detection of MAb 8E8 for affinity to some isolates collected in China.

Many properties of a protein are encoded within its sequence in a subtle and recondite manner not amendable to direct identification through sequence alignment or the recognition of characteristic sequence motifs.

This is achieved through pairwise sequence alignment of orthologous protein residues.

Multiple sets of degenerate primers were designed from the conserved domains identified in SGT's through multiple sequence alignment of SGT protein sequences retrieved from NCBI and used for isolation of partial GsSGT amplicon.

In addition, through the sequence alignment of CIDE-C domain of Cide family proteins in human and mouse (Fig 1b), we identified a highly conserved XARXTFDXYXXNPXDXXGXLNKVATXYXXYSXSXD signature in CIDE-C domain.

We must somehow map parts of the assembly back onto the reference genome through sequence alignment, which usually takes one of two forms: local alignment, exemplified by algorithms like BLAST (Altschul et al., 1997), and whole genome alignment with algorithms like MUMmer (Kurtz et al., 2004) or Mauve (Darling et al., 2004).

These observations support the results obtained through sequence alignment and evidence an occurrence of negative pressure upon non-synonymous mutations in PSL genes.

Through sequence alignment and epitope prediction, a series of highly conserved stem fragments (spanning 47 years) were found and coupled to the Keyhole Limpet Hemocyanin (KLH) protein.

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Expert writing Tips

Best practice

When using "through sequence alignment of", ensure that it clearly connects the method (sequence alignment) to the outcome or discovery it facilitates. For example, "Evolutionary relationships were determined "through sequence alignment of" conserved genes".

Common error

Avoid using "through sequence alignment of" when a more direct preposition like "using" or "via" would be clearer. For instance, instead of "errors identified "through sequence alignment of" the reads", prefer "errors identified using sequence alignment of the reads".

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

80%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "through sequence alignment of" functions as an instrumental prepositional phrase, indicating the means by which an action is performed or a result is achieved. As Ludwig AI says, it is a functional phrase in scientific or technical contexts.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, "through sequence alignment of" is a grammatically correct instrumental prepositional phrase predominantly used in scientific and technical writing. As Ludwig AI indicates, it describes a method for analyzing biological sequences. Although examples are rare, the phrase maintains a high level of source quality and expert rating, showing its relevance in specialized contexts. Alternatives like "via sequence alignment of" and "using sequence alignment of" can provide stylistic variations. Ensure that the context emphasizes sequence alignment as the direct means for achieving a specific analytical outcome.

FAQs

What does "through sequence alignment of" mean?

The phrase "through sequence alignment of" indicates that sequence alignment is the method or process by which something is achieved or understood. It's commonly used in scientific contexts to describe how data is analyzed.

What are some alternatives to "through sequence alignment of"?

You can use alternatives like "via sequence alignment of", "using sequence alignment of", or "by means of sequence alignment of" depending on the specific context.

How do I use "through sequence alignment of" in a sentence?

Ensure the phrase connects the action of sequence alignment to the result or conclusion. For example: "Conserved regions were identified "through sequence alignment of" multiple genomes".

Is there a difference between "through sequence alignment of" and "with sequence alignment of"?

"Through sequence alignment of" implies a process leading to a result, while "with sequence alignment of" suggests that sequence alignment is a tool used in conjunction with something else. The choice depends on whether alignment is the primary method or a supporting technique.

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Authority and reliability

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Real-world application tested

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