based on sequence alignment of

USAGE SUMMARY

The phrase "based on sequence alignment of" is correct and usable in written English.
You can use it when discussing research or analysis that relies on comparing sequences, such as DNA, RNA, or protein sequences. Example: "The results of our study were based on sequence alignment of the genetic material from various species."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

5 human-written examples

Based on sequence alignment of Bbp, SdrG and ClfA (Davis et al., 2001; Josefsson et al., 1998), we engineered a plasmid that would generate a recombinant fusion protein covering residues Asn273 Pro598 of Bbp from S. aureus, a segment containing both N2 and N3 domains (Fig. 1A), with N-terminal GST-tag for purification purposes in Escherichia coli.

Protein & Cell

Therefore, the accuracy for predicting the phenotype that results from an amino acid substitution based on sequence alignment of protein family members has been assumed to be better than using a generalized substitution scoring matrix [65].

Plosone

One noticeable feature regarding Mtb HupB, based on sequence alignment of HU orthologs from different bacteria, was that HupBMtb bears at its C-terminal end, a highly basic extension and this prompted an examination of its role in Mtb HupB function.

Plosone

Preliminary nemertean-specific primers (N12SF, N16SR, NCOX2R) were designed based on sequence alignment of four mitochondrial genome sequences (Cephalothrix hongkongiensis, Cephalothrix. sp., Lineus viridis, and Paranemertes cf. peregrina) retrieved from Genbank.

BMC Genomics

Following a draft de novo assembly, phylogenetic assignments were carried out based on sequence alignment of the Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCo) large subunit, RbcL (Fig.  4b, " Methods").

Biotechnology for Biofuels

Human-verified similar examples from authoritative sources

Similar Expressions

55 human-written examples

The conservation scores were generated based on sequence alignments of 16 vertebrate genomes with the human genome.

Plosone

Based on sequence alignments of H5N1 and sequencing results (data not shown) from all the isolates, a set of sequencing primers were designed spanning a region of the HA informative with regards to clade, strain, receptor binding motif, cleavability and glycosylation (Figure 1) and which specifically hybridize to H5N1.

Plosone

Trees were constructed based on sequence alignments of DNA binding domains for ERF and NF-YA and complete sequences for C2H2 and GRAS.

BMC Plant Biology

The BE403717 sequence was used to blast against the wheat genomic DNA databases (http://www.cerealsdb.uk.net), and the wheat sequences retrieved from the databases were grouped based on sequence alignments of the homoeologous and paralogous OPR genes.

BMC Genomics

Orthologous specific primers to amplify A2 members of the S H 3-CNL family from wild Coffea species were designed based on sequence alignments of A2 members in C. canephora and C. arabica: A2_Left: 5'-CCTTGATAAGAAACATGAATGAAATACACGA-3' and A2_right 5'-AAGGATAAATGAGAAGAACTACTGAGCCTG-3'.

BMC Genomics

In this study, we developed a single RT-PCR test for detecting the 3 HPeV types based on sequence alignments of HPeV-1, -2, and -3 reference strains and various clinical HPeV isolates.

Emerging Infectious Diseases

Expert writing Tips

Best practice

When writing scientific articles, clarify which sequences were aligned and the specific parameters used for the alignment to ensure reproducibility.

Common error

Avoid vague statements. Always specify the type of sequence (DNA, RNA, protein), the source of the sequences, and the alignment method used (e.g., BLAST, ClustalW) when you mention "based on sequence alignment of".

Linguistic Context

The phrase "based on sequence alignment of" functions as a prepositional phrase modifying a noun or clause. It indicates the foundation or evidence upon which a conclusion, method, or observation is grounded. Ludwig's examples show its use in scientific contexts.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, the phrase "based on sequence alignment of" is a grammatically correct and specialized prepositional phrase primarily used in scientific writing. Ludwig AI indicates that while usage is valid, it's relatively rare, primarily appearing within the science domain. When using this phrase, specifying the sequences, methods, and parameters is crucial for clarity and reproducibility. Consider alternative phrasing for broader audiences.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

derived from sequence alignment of

Stresses the origin of results from sequence alignment data.

according to sequence alignment of

Emphasizes agreement with the alignment results, rather than the foundation upon which something is built.

as determined by sequence alignment of

Focuses on sequence alignment as the method of determination.

informed by sequence alignment of

Implies that sequence alignment provided insight or direction.

inferred from sequence alignment of

Highlights the deduction made based on the alignment.

predicated on sequence alignment of

Highlights that the statement or finding is fundamentally reliant on sequence alignment.

from a sequence alignment of

Focuses on the sequence alignment as the origin of the information.

using sequence alignment of

Highlights the tool or method employed to produce the alignment.

drawing from sequence alignment of

Suggests that the information is extracted or gathered from sequence alignment.

with reference to sequence alignment of

Indicates that sequence alignment was consulted for context or support.

FAQs

How can I rephrase "based on sequence alignment of" in scientific writing?

You can use alternatives such as "derived from sequence alignment of", "inferred from sequence alignment of", or "as determined by sequence alignment of", depending on the specific context.

What information should I include when stating something is "based on sequence alignment of"?

Specify the sequences being aligned (e.g., gene names, protein families), the alignment method (e.g., ClustalW, BLAST), and any relevant parameters or databases used. This ensures clarity and reproducibility.

Is it appropriate to use "based on sequence alignment of" in non-scientific contexts?

While grammatically correct, "based on sequence alignment of" is highly technical and generally only suitable for scientific or technical writing. Simpler phrases like "according to" or "based on" are more appropriate for general use.

What's the difference between "based on sequence alignment of" and "using sequence alignment"?

"Based on sequence alignment of" implies that the alignment results are the foundation for a conclusion. "Using sequence alignment" simply means that sequence alignment was a method employed in the process, without necessarily being the sole basis for the outcome.