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Based on the results obtained by functional analyses of CEACAM1 using purified immune cells one would expect an enhanced NK, T and B cell response in Ceacam1−/− mice, favoring the control of MHV-68 infection.
We confirmed the role of several candidate genes in alcohol sensitivity by functional analyses of mutations and gene expression levels.
MiR-1 and miR-133a showed potential role of tumour suppressors by functional analyses of BC cells such as cell proliferation, apoptosis, migration, and invasion assays.
This was confirmed by functional analyses of Jc-GGPPS in GGPPS-deficient mutant plasmids, which showed the influence of Jc-GGPPS on carotenoid biosynthesis and as general precursor for diterpene biosynthesis [ 40].
Although the analysis of the P450 gene family evolution within the genus Drosophila has been informed by functional analyses of P450s (particularly in D. melanogaster), the reverse is also true, in that the evolutionary analyses informs us about P450 function.
Similar(55)
By functional analyses and BLAST searches of the TIGR rice database, a maximum number of 243 proteins that possibly have EF-hand motifs were identified in the rice genome.
By systematic functional analyses of the candidate genes, we found that longitudinals lacking (lola), a gene downregulated by innervation, plays a prominent role in the transcriptional control of a number of postsynaptic components.
This remarkably early and rapid development of the zebrafish circadian timing system is particularly intriguing and has been instrumental for the investigation of this system, for example, by enabling functional analyses of genes in intact developing fish.
As translational control is also regarded as an important mechanism for cell cycle regulation, it is possible to obtain new insight into cell cycle regulation in the G2 phase by performing functional analyses of these ribosomal proteins.
Its enzymatic activity was confirmed by functional analyses.
Second, their conclusion was not verified by functional analyses.
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