All strokes in the VBB are characterized by functional changes on the part of the brain stem structures predominantly at the pontomedullary and pontomesencephalic levels.
Similarly, in the postmeiotic eggs, the structural changes of the cortical actin networks induced by GDPβS were accompanied by the functional changes of the InsP3-dependent Ca2+-releasing mechanism, as judged by the changes of the kinetics in the Ca2+ rise (Fig. 4).
A companion study complements the microbial data by measuring functional changes of the fish and benthic communities [18].
The mutations studied here rather act by inducing functional changes of the acto-myosin interactions and, therefore, of the whole sarcomere [ 15, 17, 36].
This hyperalgesia was reflected by functional changes in pain-related areas of the brain (55).
The initial phase, neurogenic pain, is occurred by C-fiber activation produced by direct stimulation of nociceptive neurons; while the second phase, inflammatory pain, is caused by local tissue inflammation and also by functional changes in the dorsal horn of the spinal cord [ 22, 24].
These data indicate that the molecular phenotypic changes induced by MMF are accompanied by functional changes that are consistent with the phenotype of microglia involved in the maintenance of CNS homeostasis such as phagocytosis in the absence of inflammatory responses.
However, we conclude that the timing pattern observed in AD participants could be well explained by functional changes taking place at different levels of the SET model: both clock, memory and decisional mechanisms might be impaired in AD.
Ischemic brain damage is an extremely complex multi-factor, multi-level pathological process accompanied by structural and functional changes of blood-brain barrier (BBB) [ 1].
