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ARGONAUTE1 (AGO1) regulates floral meristem and organ identity by affecting expression of LEAFY, APETALA1 and AGAMOUS genes.
While it is reasonable to assume the SNP somehow affects risk for PSP by affecting expression of EIF2AK3, it remains to be proven.
One of these SNPs, CFA10 11,364,385, is found within a conserved element and is a good candidate for influencing body mass by affecting expression of HMGA2.
To assess whether exogenous p190B expression may increase tumor multiplicity by affecting expression of the Neu transgene Western blotting was performed on pooled lysates prepared from rtTA/Neu and p190B tumors (n =11 tumors per genotype).
As proposed under the gene regulation model of phenotypic plasticity [ 47], such QTL may represent regulatory loci, controlling plasticity by affecting expression of genes with a direct effect on phenotype.
(9) Moreover, evidence has suggested that NPAS2 may play an important role in tumorigenesis by affecting expression of cancer-related genes and could be considered as a novel tumor suppressor.
Similar(53)
Taken together, these results suggest that virB mediates Brucella survival by affect expression of other genes and modifying signaling pathways of host cells.
A number of miRNAs were shown to interfere in apoptosis by affecting expression and activation of effector caspases.
To determine if the knock-down of ADAM10 by siRNA affects expression of E-cadherin, the cells were transfected with medium only, the empty vector, the control siRNA, or siRNA against ADAM10.
It was known that microRNAs could regulate a variety of cellular pathways by affecting the expression of multiple types of target genes and the alteration of microRNAs expression might contribute to human carcinogenesis [ 9, 11, 12].
Altogether, these data suggest that microenvironmental signals, such as HGF, may modulate the phenotype of luminal progenitors, by affecting the expression of antagonistic regulators of the basal and luminal fates.
Related(20)
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