Sentence examples for binding to human colonic from inspiring English sources

Glycoproteins, not gangliosides, are responsible for the majority of CTB binding to human colonic epithelial cell lines.

10.7554/eLife.09545.009 Figure 4. CTB binding to human colonic epithelial cell lines depends on protein glycosylation.

10.7554/eLife.09545.018 Figure 7. Aleuria aurantia lectin (AAL) blocks CTB binding to human colonic epithelial cell lines.

10.7554/eLife.09545.019 Figure 8. Inhibition of fucosylation reduces CTB crosslinking and binding to human colonic epithelial cell lines.

In summary, we demonstrate that fucosylated glycoproteins mediate a large portion of CTB binding to human colonic epithelial cell lines, that fucosylated glycoproteins play an important role in the mechanism by which CTB enters T84 cells, and that entry of CT into T84 cells via a fucose-dependent mechanism is on-pathway to host cell intoxication.

Fucose blocks binding of CTB to human colonic epithelial cell lines.

Colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH) is histologically, morphologically, and anatomically similar to human colonic epithelial neoplasms [ 14].

(C and D ) CTB binding to freshly isolated human colonic epithelial cells (LIVE/DEAD-CD45 EpCAM+) assessed by flow cytometry.

To test these ideas, BtMinpp-containing OMVs were added to HT29 human colonic epithelial cells in the absence of extracellular calcium.

Antagonists to EP1 receptor have also been studied for their ability to reduce human colonic longitudinal muscle contractility in vitro [ 29].

We obtained ethics approval from the Ethics Committee of the Medical Faculty of the University of Leipzig (No111-2009) to analyze human colonic samples and written consent from all participants involved in this study.