Sentence examples for binding to human plasma from inspiring English sources

Figure 1 Effects of silica particle size on binding to human plasma proteins.

Figure 3 Effects of surface modification of silica particles on binding to human plasma proteins.

We also evaluated the effect of the specific surface area of the silica particles on binding to human plasma proteins.

Figure 2 Effects of the specific surface area of silica particles on binding to human plasma proteins.

It had been determined previously that the extent of edivoxetine binding to human plasma protein was approximately 65%% and drug concentration independent.

Based on pharmacokinetic modelling data demonstrating high drug binding to human plasma proteins, an optimised dosing schedule of 30-min i.v. bolus (IVB) followed by 4-h CIVI has been pursued.

This concentration has to be compared to its pharmacological concentration, taking into account its binding to human plasma-proteins which was found to be 33% at 20 ng·mL−1 and no saturation was observed until 5000 ng·mL−1 (unpublished observations).

The results showed that there was no significant difference in binding with each protein among each size of silica particle tested (Figure 2A,B,C,D), suggesting that the binding of silica particles to human plasma proteins is dependent on the specific surface area of the silica particles.

Protein binding and binding to human serum albumin are greater than 98%, and the plasma half-life is short (approximately 1 hour).

Annexin V binding to human umbilical vein endothelial cells was assessed by flow cytometry after 24-hour culture with plasma.

Febuxostat is highly (>98%) bound to human plasma proteins, mainly at the diazepam binding site.