Sentence examples for binding to human serum from inspiring English sources

The feature of its binding to human serum albumin (HSA) was also investigated under simulative physiological conditions via fluorescence and UV vis absorption spectroscopy and molecular modeling methods.

Within this paper, a number of calibration approaches are investigated and tested using warfarin binding to human serum albumin as a model system.

The predicted plasma-protein binding has been estimated by the prediction of binding to human serum albumin; the (log K_{text{HSA}}) parameter (the recommended range for 95% of known drugs is −1.5 to 1.5).

The pressure shift assay (PSA, also termed either PressureFluor or differential pressure fluorimetry) was used to study the thermodynamics of decanoate and dodecanoate lipid binding to human serum albumin (HSA) in the temperature range from 25 °C to 80 °C and the pressure range from 0.1 MPa to 400 MPa.

Recently, the dissociation constants for PFOA binding to human serum albumin (HSA) and the number of PFOA binding sites on HSA were determined (Han et al. 2003).

The second domain was designed to improve the pharmacokinetic (PK) properties of the Nanobody by binding to human serum albumin (HSA).

For example, the number of PFOA binding sites to human serum albumin (HSA) was found to be over 6 and more than 90% of PFOA would be bound to HSA in human blood.

This study was designed to investigate the binding of genistein to human serum albumin (HSA) under physiological conditions with drug concentrations in the range of 6.7 × 10−6 to 2.0 × 10−5 mol L−1 and HSA concentration at 1.5 × 10−6 mol L−1.

(1251) The binding of sulfonamides to human serum albumin (HSA) and the consequent drug inactivation were observed in the early 1940s.

In this paper, the enantioselective binding of propanocaine (PRO) enantiomers to human serum albumin (HSA), the most relevant plasmatic protein in view of stereoselectivity, has been evaluated by incubation and ultrafiltration of racemic PRO HSA mixtures and chiral analysis of the bound and unbound fractions by electrokinetic chromatography using HSA as chiral selector.

It is reasonable to believe that this low binding property may be extrapolated to human serum albumin [ 41].