Sentence examples for activation and release from inspiring English sources

Different animal models, as well as proteomics approaches for the identification of protease substrates, have helped to reveal more precise molecular signalling events mediated by meprin activity, such as activation and release of pro-inflammatory cytokines.

Postsynaptic PKC is activated following strong NMDAR activation and release of Ca2+ from intracellular stores, experimentally achieved by stronger, repetitive LTP induction paradigms (Bliss & Collingridge, 1993; Raymond, 2007).

Second, the dynamic uptake of the prodrug by activated synoviocytes and subsequent trafficking to an acidic lysosomal compartment provides an environment in which there is gradual local prodrug activation and release of active drug resulting in sustained anti-inflammatory signaling through blockade of proinflammatory cytokine production.

The enzymatic activity of caspases has also been associated with the proper activation and release from the mitotic checkpoint.

Platelet activation and release of biomolecules such as PF-4 from activated platelets is influenced by the presence and interaction of leukocytes with platelets.

It increases vascular permeability in vivo and activates endothelial cells in vitro, leading to protein kinase C activation and release of several proteins for which plasma levels are elevated in vivo due to diabetic endothelial dysfunction (6, 14).

Importantly, early microglial activation and release of inflammatory signals, such as IL-1β, can activate CD3 T-cells and initiate a cascade resulting in astrocyte secretion of TNFα, chemokines and ROS (reactive oxygen species) that induce demyelination at 3 4 weeks after initiation of cuprizone (Kang et al., 2012).

DBM contains the collagen necessary to activate PRP, but in amounts small enough to create a slower, more sustained activation and release of PRP growth factors than the thrombin activation [ 37].

Special fields for SPS activation and release for PDCCH validation are illustrated in Tables 2 and 3 [19].

Gestural controls in VR seem to be good at reading orientation (is my hand up, down, tilting) but bad at reading exact points of activation and release.

In our study, indeed, MSCs dampened leukocyte trafficking through the alveolar epithelial barrier as well as their activation and release of primary inflammatory cytokines.