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Macrophages that ingest LDL-ICs become activated and release TNF-α, IL-1, oxygen-activated radicals, and matrix metallo-proteinase-1 [ 86].
Upon re-exposure to that antigen, mast cells are activated and release preformed mediators such as histamine and newly formed mediators such as leukotrienes.
The results of such simulations (Figure 5) support the hypothesis that the initiation of the positive feedback loop results from a very small number of cells that are activated and release interferon at early time-points.
Immediately after starting HD treatment, PLTs are being activated and release their content.
In the course of GPR30 signaling, certain membrane bound matrix metalloproteases are activated and release EGF from the extracellular matrix.
Both Mφ and peripheral blood monocytes (MO) are activated and release proinflammatory cytokines (IL-1β, tumour necrosis factor [TNF] alpha).
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Once bound by ligand, the androgen receptor is activated and released from this protein complex, allowing the formation of homodimers (or potentially heterodimers) that bind to DNA at palindromic androgen response elements (AREs) in androgen responsive gene promoters.
Once the toxin is activated and released, it causes paralysis by increasing neurotransmitter release at invertebrate neuromuscular junctions.
If there is a local inflammatory response and PMN infiltration following subretinal delivery of nanoparticles, MPO will be activated and released.
During bleeding to restore homeostasis, the sympathetic nervous system becomes activated and releases epinephrine and norepinephrine.
These factors attract neutrophil infiltration, which were activated and released more inflammatory factors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com