Sentence examples for activation and gene from inspiring English sources

IL-10, on the other hand, activates STAT3-mediated alternative activation and gene expression [7],[7]]-[7]].

In this work, we propose a model where in cancer cells with basal levels of KSR1, phosphorylated DBC1 directly interacts with SIRT1 and reduces its deacetylase activity resulting in p53 activation and gene expression initiation.

However, although the depletion of AP2M1 blocked transferrin uptake to the same extent as CHC knockdown, it failed to increase basal IκBα degradation (Figures 4C and 4D) and IL-8 secretion (Figure 4E), suggesting that CHC controls basal NF-κB activation and gene expression independently of its activity in CME.

To assess the diverse aspects of GR mechanisms of activation and gene regulation, researchers continue to use a range of artificial GR mutants.

The kinetics of protein downregulation is therefore determined by the complex interaction of both ligand chemistry (nuclease stability, affinity and RNase H activation), and gene expression kinetics.

However, that assay doesn't pinpoint the moment of activation or provide a straightforward way to quantify the connections between microglial activation and gene expression patterns.

Therefore, we combined in vitro and in vivo approaches to study HIF-1α activation and gene-transcription during RSV infection.

We conducted a comprehensive analysis of cytokine and chemokine activation and genes representative of the inflammatory processes in PsA.

For these reasons it is speculated that the retroviral system may be more prone to adverse gene activation, and such gene activation results from the activation of the downstream genes by the long terminal repeats (LTRs) within these vectors [45], [46].

Collectively, our global gene expression analysis supports broad roles for Brg1 in gene activation and maintaining gene repression of key developmental regulators during mesoderm differentiation of ESCs.

The trans-activation and gene regulatory potential of B-MYB is regulated by cyclin A/cdk2-mediated phosphorylation [8], and B-MYB is degraded through a ubiquitin-mediated process late in S phase [9].