Sentence examples for activation and cytotoxicity from inspiring English sources

TNF-α antagonists, including antibodies, have been developed for binding to TNF-α as a mean to inhibit its biological activities, including TNF-α-induced cell activation and cytotoxicity.

Reductive activation and cytotoxicity of prodrugs were measured using mass spectrometry and antiproliferative assays, respectively.

Despite the increasing body of evidence showing NK cell involvement in the control of HIV infection, HIV can affect NK cell phenotype and function during HIV infection, including the cytokine/chemokine production, activation, and cytotoxicity of NK cell subsets.

Forced expression of FOXRED2 increased SN29428 activation and cytotoxicity in hypoxic HEK293 cells and also increased activation of hypoxia-targeted prodrugs PR-104A, tirapazamine and SN30000, and increased cytotoxicity of the clinical-stage prodrug TH-302.

LA also suppressed NK cell activation and cytotoxicity.

DC undergoing maturation secrete several cytokines, such as IL-12 and IL-18, that act as potent inducers of NK cell activation and cytotoxicity [16] [20].

Muscle injury typically induces a local increase in MPO activity that reflects neutrophil activation, extravasation, and cytotoxicity.

It is a very effective mechanism, which helps in mass destruction of virus-infected cells by using antibodies (antibody-dependent cell mediated cyto-toxicity ADCC system), classical pathway of complement activation, phagocytosis, and cytotoxicity mediated by CD8+ lymphocytes.

Next, to assess the combination effects of the CEBPD and granzyme B prodrugs in PrCa cells, caspase activation and the cytotoxicity were measured.

Moreover, splenocyte activation and CTL cytotoxicity assays in these experiments suggested that fibroblasts are an efficient alternative to tumour cells for neuroblastoma vaccination.

Activation, cytokine release and cytotoxicity of NK cells stimulated by monocytes and PstS-1 were determined by FACS-analysis, ELISA, Bioplex assay and quantitative polymerase-chain reaction (qPCR).