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The tumor staining intensity was calculated using following formula; tumor intensity = (post-injection tumor intensity) – (pre-injection tumor intensity).

While some tumor accumulation was observed for VCN, tumor intensity for A192-VCN was detected earlier and with greater intensity.

The tumor-background ratio (TBR) was calculated using the following formula; TBR = (post injection tumor intensity)/(post injection back ground intensity).

Consider a scenario where the reference signal is computed as an average (median) of tumor intensity signals instead of traditional average of normal reference samples intensities.

The sublibrary pool with the most significant p-value and increasing tumor intensity was partitioned and regrown in 3,000 microtiter wells.

The tumor intensity levels from 0 to 3 are shown in Figure  1A and extent from 1 to 3 on Figure  1B.

Similar(54)

The fluctuating intra-tumor intensity illustrates the heterogeneity of tumor tissue, containing both viable (hyper-intense) and necrotic (hypo-intense) regions.

Each of the TNFα- and IL-1β-positive tumors were analyzed for % positive cells in the tumors, intensity of expression of the cytokines, and score (as described in "Materials and methods").

Therefore, alternative metabolic parameters that integrate both tumor volume and intensity of uptake may provide more precise clinical information.

Standardized fluorescence values (in picomoles/mm3) were calculated by dividing the total tumor fluorescence intensity by the tumor volume assessed by caliper.

Tumor fluorescence intensity reached a maximum at 6 h post-injection with good contrast.

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