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'tumor microenvironment' is correct and usable in written English.
Generally, you can use it when referring to the environment around a tumor that affects how the tumor behaves. For example, "The tumor microenvironment can play an important role in tumorigenesis."
Exact(60)
Cancer genome and tumor microenvironment.
TAM, tumor-associated macrophages; TME, tumor microenvironment.
The tumor microenvironment contains abundant cytokines.
Tumor microenvironment and therapeutic resistance process.
Genetic instability induced by the tumor microenvironment.
Sautès-Fridman, C. et al. Tumor microenvironment is multifaceted.
Ostman A. The tumor microenvironment controls drug sensitivity.
Hypoxia is a common feature of the tumor microenvironment.
The role of tumor microenvironment in collective tumor cell invasion.
These conditions are typical of the tumor microenvironment.
Innate and adaptive immune cells in the tumor microenvironment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com