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Overall our results point to a novel model of PML regulation in which USP7 triggers degradation of PML by a mechanism that does not require phosphorylation of PML by CK2 or polyubiquitylation by RNF4.
AhR does further act as an ubiquitin ligase that triggers degradation of selected proteins, as, for instance, the oestrogen receptor.
The IKK-catalysed phosphorylation triggers degradation of IκB-α leading to the release of NF-κB followed by its translocation to the nucleus where it regulates gene expression.
The proteasome is a barrel-shaped, multi-catalytic protease complex present in the cytosol and in the nuclei and triggers degradation of multi-ubiquitinated proteins [ 19].
Frameshifts change the amino acid added by the ribosome that either no longer codes for the original protein or introduces a premature termination codon that triggers degradation of the mRNA.
Ixodes scapularis is the primary vector of the Lyme disease agent in the eastern and central U.S. RNAi is a mechanism by which gene-specific double-stranded RNA (dsRNA) triggers degradation of homologous mRNA transcripts.
Similar(51)
Upon full R-loop zipping conformational changes within the RNPs trigger degradation of the DNA target.
EIS provided direct evidence of the susceptibility of the tBLMs to phospholipase A2, which triggered degradation of the films.
Both insufficient agricultural practices and periodical wildfire occurrence in abandoned areas were focused as components triggering degradation processes.
The light-absorbing molecules break off from the chains when exposed to ultraviolet light at 350 nanometers wavelength, triggering degradation of the plastics.
This letter reports a novel scheme for triggering degradation of 250 μm-thick Mg target using acetic acid regarding transient electronics applications.
Related(20)
triggers erosion
elicits degradation
triggers damage
stimulates degradation
triggers alteration
triggers impairment
initiates degradation
triggers reduction
triggers degenerative
triggers disruption
triggers destruction
triggers contamination
triggers decay
triggers depletion
onset degradation
start degradation
activation degradation
stimulated degradation
encourages degradation
induces degradation
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