triggering apoptosis

USAGE SUMMARY

The phrase "triggering apoptosis" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing the process of programmed cell death in biological systems. Example: "The drug works by triggering apoptosis in cancer cells, leading to their eventual elimination from the body."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

A lethal dose of the drug kills cells primarily by forming DNA adducts, causing G2 arrest in the cell cycle, and then triggering apoptosis.

Stanford University

Synthetic compounds mimicking such tetrapeptide motif effectively block the interaction between IAP and active caspases, thus triggering apoptosis.

Journal of Molecular Biology

CH up regulated intrinsic apoptotic pathway proteins like bax, caspase-9 and caspase-3 along with down regulation of Bcl-2 triggering apoptosis.

Archives of Biochemistry and Biophysics

It acts on prostate cell growth by causing G0/G1 phase arrest and triggering apoptosis as assessed by flow cytometry measurements.

European Journal of Medicinal Chemistry

Many potentially harmful mutations, however, increase the probability of triggering apoptosis and, hence, initially lead to cells with reduced net proliferation rates.

Journal of Theoretical Biology

Analysis of mechanisms involved in the cytotoxic activity showed that active compounds were leading to DNA damage, triggering apoptosis or necrosis induction.

European Journal of Medicinal Chemistry

JNK, as determined by its phosphorylation state, is subsequently activated, triggering apoptosis.

Duke University

The process of triggering apoptosis involves a long cascade involving molecules known as caspases.

Brain Informatics

Many of its derivatives inhibit the growth of human cancer cell lines by triggering apoptosis.

Chemistry Central Journal

Once the small molecule dimerizer chemical inducer of dimerization (CID) AP20187 is added, it binds to iCasp9, triggering apoptosis.

Protein & Cell

Triggering apoptosis of ovarian cancer cells by trastuzumab, anti-HER-2 biosimilars, and AVEC was tested by quantifying phosphatidylserine externalization detected in flow cytometry and fluorescence microscopy.

Clinical and Translational Medicine

Expert writing Tips

Best practice

When writing about the mechanisms of drugs or therapies, use "triggering apoptosis" to clearly indicate the induction of programmed cell death in targeted cells, especially in scientific and medical contexts.

Common error

Avoid using "triggering apoptosis" in contexts where cell death occurs through necrosis or other mechanisms. "Triggering apoptosis" specifically refers to programmed cell death and shouldn't be used as a blanket term for all forms of cell death.

Linguistic Context

The phrase "triggering apoptosis" functions as a verbal phrase describing the initiation of programmed cell death. It's commonly used in scientific writing to explain mechanisms of action, as confirmed by Ludwig's examples.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "triggering apoptosis" is a common and grammatically correct term used extensively in scientific and medical contexts to describe the initiation of programmed cell death. Ludwig AI indicates its widespread use in academic papers and research articles. Alternative phrases like "inducing apoptosis" or "activating apoptosis" can be used, but it's essential to maintain specificity in describing the mechanism of cell death. When writing about this topic, be mindful of the context and avoid overgeneralizing the term to encompass all forms of cell death.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

inducing apoptosis

Changes the verb to a synonym, "inducing", while keeping the core meaning intact.

initiating apoptosis

Replaces "triggering" with "initiating", focusing on the start of the apoptotic process.

activating apoptosis

Substitutes "triggering" with "activating", emphasizing the activation of the cell death pathway.

promoting apoptosis

Uses "promoting" instead of "triggering", suggesting an acceleration of the apoptotic process.

stimulating apoptosis

Replaces "triggering" with "stimulating", implying an encouragement of apoptosis.

causing apoptosis

Uses the direct causal verb "causing" instead of "triggering".

inducing cell death

Broader term that replaces "apoptosis" with the more general "cell death".

eliciting apoptosis

Uses "eliciting" in place of "triggering", indicating a response being drawn out.

leading to apoptosis

Expresses the relationship as a consequence, where "triggering" is replaced with "leading to".

setting off apoptosis

Replaces "triggering" with the more informal "setting off", maintaining the meaning of initiating.

FAQs

What does "triggering apoptosis" mean?

The phrase "triggering apoptosis" refers to the process of initiating or inducing programmed cell death. Apoptosis is a regulated process of cell self-destruction that plays a critical role in development and disease.

What are some synonyms for "triggering apoptosis"?

You can use alternatives like "inducing apoptosis", "initiating apoptosis", or "activating apoptosis" depending on the context.

How is "triggering apoptosis" used in cancer research?

In cancer research, "triggering apoptosis" is often used to describe how certain therapies or drugs work to eliminate cancer cells by inducing programmed cell death, preventing them from further proliferation.

Is it correct to say "triggering cell death" instead of "triggering apoptosis"?

While "triggering cell death" is a broader term, "triggering apoptosis" is more specific. Apoptosis is a specific type of cell death. If the mechanism is known to be apoptosis, then "triggering apoptosis" is more accurate.