Inducing apoptosis is one of the most important mechanisms of chemotherapeutic drugs to kill cancer cells.
Further, the efficacy of uttroside B in inducing apoptosis in HepG2 cells was analyzed by Flow cytometry.
Celecoxib, a specific COX-2 inhibitor, has been reported to exert chemopreventive effect by inducing apoptosis.
TX-1102 was a potent antiangiogenic hypoxic cytotoxin inducing apoptosis p53-independently.
This combination treatment showed promising results in vitro, inducing apoptosis in human melanoma cells.
Many anticancer drugs are designed to kill cells by inducing apoptosis.
DNA damage response can trigger tumor suppressor p53 activation, which ensures genome integrity of reprogramming cells by inducing apoptosis and senescence.
Zhang, N., Kong, X., Yan, S., Yuan, C. & Yang, Q. Huaier Aqueous Extract Inhibits Proliferation of Breast Cancer Cells by Inducing Apoptosis.
This localization is considered advantageous for PDT, as lysosomal photosensitizers such as EtNBS have been found capable of inducing apoptosis while simultaneously preventing autophagic rescue28.
The nongranular cytotoxic T cells often kill cells by inducing apoptosis, usually through the activation of a cell-surface protein called Fas.
Apart from this study, the morphological appearance of apoptosis was confirmed with a known cytotoxic agent inducing apoptosis (i.e., bortezomib) in synoviocytes16, inducing the same apoptotic changes.
