template strand

USAGE SUMMARY

The phrase "template strand" is correct and usable in written English.
It is typically used in the context of molecular biology to refer to the strand of DNA that serves as a template for RNA synthesis during transcription or for DNA replication. Example: "During the process of transcription, the RNA polymerase binds to the template strand to synthesize the complementary RNA molecule."

✓ Grammatically correct

Science

Encyclopedias

Academia

Human-verified examples from authoritative sources

Exact Expressions

56 human-written examples

During transcription, the non-template strand remains more exposed as single-stranded than the template strand, which causes asymmetry in cytosine deamination between the strands.

DNA Research

This is called the template strand, and the RNA molecules produced are single-stranded messenger RNAs (mRNAs).

Britannica

But now and here's the template strand.

Cornell University

The AAA+ modules only make contact with the template strand (yellow).

University of California, Berkeley

It has also been suggested that G-quadruplexes forming on the coding or non-template strand, as is the case with the C9orf72 repeats, could enhance transcription by keeping the template strand single stranded26.

Nature

DNA polymerase requires a primer that can bind to a known region of the template strand.

Encyclopedia Britannica

If it's the right one, it plunks it in place, moves along the top template strand, and it works.

Cornell University

Human-verified similar examples from authoritative sources

Similar Expressions

4 human-written examples

The T + 1 nucleotide (lemon green) is base-paired with the non-template strand and more than 30 Å away from the RNAP active-site Mg2+.

Nature

During transcription, the nascent RNA strand can base pair with its template DNA, displacing the non-template strand as ssDNA and forming a structure called an R-loop.

Stanford University

Telomeric repeats are transcribed in vivo, and the G-rich strand is the non-template strand [48], [49].

Plosone

a, Protein DNA interactions for template-strand DNA of RPo.

Nature

Expert writing Tips

Best practice

When discussing gene expression, clearly specify that the "template strand" serves as the mold for RNA synthesis to avoid confusion with the coding strand.

Common error

Avoid using "template strand" and coding strand interchangeably. Remember that the template strand is the one RNA polymerase reads, and its sequence is complementary to the mRNA, whereas the coding strand has the same sequence as the mRNA (except for T/U differences).

Linguistic Context

The phrase "template strand" functions as a noun phrase, specifically identifying a strand of DNA that serves as a template during RNA synthesis. Ludwig confirms its proper usage in molecular biology contexts.

Expression frequency: Common

Frequent in

Science

75%

Academia

15%

Encyclopedias

10%

Less common in

News & Media

0%

Formal & Business

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, "template strand" is a noun phrase accurately and frequently used within the scientific and academic fields to denote the DNA strand that serves as a template for RNA synthesis. Ludwig AI analysis confirms its correct usage, especially in academic and scientific contexts. It's crucial to differentiate it from the coding strand to avoid confusion. Remember to use "non-coding strand" or "antisense strand" as alternatives and always specify the role of the template strand in gene expression.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

non-coding strand

This alternative highlights the function of the strand as the one not directly coding for a protein.

antisense strand

Focuses on the strand's role as being complementary to the coding or sense strand.

transcribed strand

Emphasizes the strand's role in being the one that is transcribed into RNA.

mRNA template

Specifies the template used for messenger RNA synthesis.

DNA template

A more general term referring to the DNA strand serving as a template.

guide strand

Highlights the role of the strand as guiding the synthesis of a new strand.

minus strand

Refers to the strand with a negative polarity in relation to the coding strand.

negative strand

Another term for the minus strand, indicating its complementary nature.

non-template sequence

Focuses on the sequence of the strand, clarifying that it's not the template itself.

complementary DNA strand

Highlights the fact that the strand is complementary to another DNA strand.

FAQs

What is the role of the template strand in transcription?

During transcription, the "template strand" of DNA serves as a guide for RNA polymerase to synthesize a complementary RNA molecule.

What is the difference between the template strand and the coding strand?

The "template strand" is read by RNA polymerase, while the coding strand has the same sequence as the mRNA (except T is replaced by U).

Can I use "non-coding strand" instead of "template strand"?

"Non-coding strand" is often used interchangeably with "template strand", as it highlights the fact that this strand does not directly code for a protein.

How does the template strand relate to the mRNA sequence?

The mRNA sequence is complementary to the "template strand", meaning that where the template strand has an A, the mRNA will have a U; where the template strand has a G, the mRNA will have a C, and so on.