Sentence examples for target for suppression from inspiring English sources

MPS I-H represents a good target for suppression therapy because the majority of MPS I-H patients carry nonsense mutations, and restoration of even a small amount of functional α-l-iduronidase may attenuate the MPS I-H phenotype.

Collectively, our data identify PDE8 as a novel target for suppression of Teff cell functions, including adhesion to endothelial cells.

Thus, MCP-1 appears to be a potential therapeutic target for suppression of myocardial inflammatory responses and for protection of cardiac function in the elderly with endotoxemia.

In addition, it predicts that the IAP protein could serve as a potential therapeutic target for suppression of the cell-to-cell variation in the intrinsic apoptosis responsiveness.

These results provide the first evidence that MMP28 plays an important role in tumor invasion and metastasis and suggest MMP28 may be an effective target for suppression of metastasis in gastric cancer.

When girls' and women's freedom of speech is so disproportionately targeted for suppression and when challenges to our freedom of expression are ignored or treated as trivial and inconsequential, or a problem we're expected to solve individually, public life and democracy are degraded.

Since Treg are present at relatively high frequencies in both tumor tissue and LN (Figure 1B), we hypothesized that one of their targets for suppression would be resident DC.

This would simplify choosing other targets for suppression of P. vulnus.

In a similar fashion, if the IFNβ (Ifnb1) transcript itself was targeted for suppression, it might also be predicted to have a direct effect on downstream expression of type I IFN-induced genes (as also observed in this study).

The target gene to be silenced can include a single gene or part sequence of a single gene that is targeted for suppression or can include multiple consecutive segments of a target gene, multiple nonconsecutive segments of a target gene, multiple alleles of a target gene, or multiple target genes from one or more species.

The present study demonstrates proof of concept for the approach of using short interfering RNAs with at least partial complementarity to two target transcripts for suppression of the expression of unrelated genes.