Sentence examples for target for repression from inspiring English sources

Recent work has identified the pro-apoptotic gene APAF1 as a likely target for repression by HDAC2, providing a specific mechanism for both HDACi efficacy and resistance in HDAC2 mutant cells, where HDACi does not appreciably alter APAF1 levels (Hanigan et al., 2008).

It drives auto-regulation of sc in the SOP itself and is probably a target for repression in the inhibited cells.

We also show in the present study that a CDKI [CDK (cyclin-dependent kinase) inhibitor] gene, p21, is a target for repression by Oct-4.

In addition, we also showed in the present study that the p21 gene is a target for repression by Oct-4 in ZHBTc4 ES cells.

Senescence was accompanied by induction of the cyclin-dependent kinase inhibitor-encoding genes p16, a known tumor suppressor, and p21, a previously described target for repression by AP4.

As RyhB is itself a target for repression by Fur, there is an apparent positive regulation of these genes by Fur.

Importantly, our PRC2 subunit organization is consistent with previously proposed models of PRC2 activity (Margueron et al., 2009; Schmitges et al., 2011): when chromatin domains are targeted for repression, PRC2 is recruited to deposit the repressive H3K27me3 histone mark at nucleosome-associated regions of DNA.

"For people who have gone through a stop-and-frisk search, as well as the experience of African-Americans of the early 20th century or labor activists who had been targeted for repression," he said, "marching in silence is a way to emphasize just how well behaved and dignified they can be.

Like the Hmong, the Montagnards may be targeted for repression in part because many of their parents and grandparents fought alongside American and South Vietnamese troops in the Vietnam war.Any perceived minority challenges to Kinh hegemony are a "non-starter" for the government, says Stale Torstein Risa, a former Norwegian ambassador to Vietnam.

Examples of possible targets for repression by Kaiso are CDKN2A [8], MMP7 [9], Rb [10], MTA2 [5], E-cadherin, mts-1 and Xist [6] in mammals, and Cyclin D1, Siamois, c-Fos, c-Myc [11] and Wnt-11 [12] in Xenopus.

Specific species regulating non-canonical Wnt signalling conferred growth inhibition when targeted for repression in these EC cells.