Sentence examples for subtle defect from inspiring English sources

The spt16-m allele contains two amino acids substitution (K692AR693A) in its tandem pleckstrin homology (PH) domain and displays a subtle defect in transcription initiation but a substantial defect in DNA replication-coupled nucleosome assembly (Yang et al., 2016).

Thus, the possibility remains that there is a subtle defect in the UNG-Mre11-pol η pathway (Fig. 4).

However, our results showing the lack of even a subtle defect with the cdc24 mutant bearing 35 phosphorylation site mutations suggest that much of the phosphorylation on Cdc24 is dispensable for its function.

It is interesting that inhibition of the fourth yeast subunit, Mvb12p, also exhibits a relatively subtle defect in comparison to loss of the other ESCRT-I subunits [17] [20], exhibiting only a partial defect in MVB sorting.

A Dscam mutation in mice leads to a subtle defect in the caudal folium of the cerebellum [ 42].

A subtle defect in centromere cohesion detected at these neocentromeres may be due to the paucity of heterochromatin domains.

In incrosses of atp1a3a tpl10 heterozygotes we did not observe embryos with severely dilated (or otherwise morphologically defective) brain ventricles, but we have not assessed them for more subtle defects (Additional file 7: Figure S5A).

Minor anomalies are subtle defects of appearance and structure evaluated subjectively or by measurement.

FOXP2 first came to light in a large London family, half of whose members had subtle defects in their speech and understanding.

Some diseases may consist of only extremely subtle defects in cells that render the cells more susceptible to injury in certain situations.

Infants who die in their sleep of no apparent cause often have subtle defects in an area of the brain that regulates breathing, heart rate and arousal, doctors are reporting today.